Welcome to the Glaucoma Cell Biology Laboratory at the University of Iowa Carver College of Medicine

Under the direction of Dr. Markus H. Kuehn, the main goal of the laboratory is to determine the neurobiology and the molecular events that lead to vision loss in glaucoma, but also other optic neuropathies. A second focus of our work is the development of stem cell based regenerative approaches to reverse the damage to the eye.

Research Areas 

fluorescent labeled cell layer

Neuroinflammation in Glaucoma

A major focus of the lab is to determine the role of adaptive immune responses in the pathobiology of glaucoma. Our studies indicate that T-cell mediated pre-inflammatory signaling significantly contributes to progressive vision loss in the disase. More information...

fluorescently labeled cell layer

Regeneration of the Trabecular Meshwork

Dysfunction and loss of the cells residing within the trabecular meshwork contributes significantly to the development of elevated intraocular pressure in glaucoma. We are investigating if replacing these cells with stem cells can reverse the damage. More information...