Welcome to the Glaucoma Cell Biology Laboratory at the University of Iowa Carver College of Medicine
Kuehn lab images
Under the direction of Dr. Markus H. Kuehn, the main goal of the laboratory is to determine the neurobiology and the molecular events that lead to vision loss in glaucoma, but also other optic neuropathies. A second focus of our work is the development of stem cell based regenerative approaches to reverse the damage to the eye.
Research Areas
Neuroimmunology of Glaucoma
A major focus of the lab is to determine the role of adaptive immune responses in the pathobiology of glaucoma. Our studies indicate that T-cell mediated pre-inflammatory signaling significantly contributes to progressive vision loss in the disase. More information...
Regeneration of the Trabecular Meshwork
Dysfunction and loss of the cells residing within the trabecular meshwork contributes significantly to the development of elevated intraocular pressure in glaucoma. We are investigating if replacing these cells with stem cells can restore function to the tissue and result in normal intraocular pressure. More information...